| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
* Station de Génétique Quantitative et Appliquée, Institut National de la Recherche Agronomique (INRA), Jouy-en-Josas 78352, France
Union Nationale des Coopératives agricoles d’Elevage et d’Insémination Animale, 75595 Paris Cedex 12, France
1 Corresponding author: tom.druet{at}dga.jouy.inra.fr
A marker-assisted selection program (MAS) has been implemented in dairy cattle in France. The efficiency of such a selection program depends on the use of correct genetic parameters for the marked quantitative trait loci (QTL). Therefore, the objective of this study was to estimate the proportion of genetic variance explained by 4 QTL described in previous studies (these QTL are segregating on chromosomes 6, 14, 20, and 26). Genotypes for 11 markers were available for 3,974 bulls grouped within 54 sire families of the French Holstein population undergoing MAS. The parameters were estimated for 4 QTL and 5 dairy traits: milk, fat and protein yields, and fat and protein percentages. The proportion of genetic variance explained by the QTL ranged from as low as 0.03 to 0.36%. Both lack of marker informativity and poor monitoring of QTL transmission might limit the accuracy of estimation. The QTL explained a larger proportion of genetic variance for milk composition traits. The QTL on chromosome 14 and chromosomes 6 and 20 have their largest influence on fat and protein percentages, respectively. The overall proportions of genetic variance explained by the QTL were 27.0, 30.7, 24.1, 48.2, and 33.6% for milk, fat and protein yields, and fat and protein percentages, respectively. These results clearly indicated that a large part of the genetic variance is explained by a small number of QTL and that their use in MAS might be beneficial for dairy cattle breeding programs.
Key Words: genetic parameter • quantitative trait locus • dairy trait • marker-assisted selection
This article has been cited by other articles:
|
|
 |
|
  S. Neuner, R. Emmerling, G. Thaller, and K.-U. Gotz Strategies for Estimating Genetic Parameters in Marker-Assisted Best Linear Unbiased Predictor Models in Dairy Cattle J Dairy Sci, November 1, 2008; 91(11): 4344 - 4354. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. P. P. Macciotta, M. Mele, G. Conte, A. Serra, M. Cassandro, R. Dal Zotto, A. Cappio Borlino, G. Pagnacco, and P. Secchiari Association Between a Polymorphism at the Stearoyl CoA Desaturase Locus and Milk Production Traits in Italian Holsteins J Dairy Sci, August 1, 2008; 91(8): 3184 - 3189. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Guillaume, S. Fritz, D. Boichard, and T. Druet Short Communication: Correlations of Marker-Assisted Breeding Values with Progeny-Test Breeding Values for Eight Hundred Ninety-Nine French Holstein Bulls J Dairy Sci, June 1, 2008; 91(6): 2520 - 2522. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. M. Sellner, J. W. Kim, M. C. McClure, K. H. Taylor, R. D. Schnabel, and J. F. Taylor BOARD-INVITED REVIEW: Applications of genomic information in livestock J Anim Sci, December 1, 2007; 85(12): 3148 - 3158. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Gautier, A. Capitan, S. Fritz, A. Eggen, D. Boichard, and T. Druet Characterization of the DGAT1 K232A and Variable Number of Tandem Repeat Polymorphisms in French Dairy Cattle J Dairy Sci, June 1, 2007; 90(6): 2980 - 2988. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
