JDS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 QUICK SEARCH:   [advanced]


     


This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Interpretive Summary
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Schulman, N. F.
Right arrow Articles by Vilkki, J. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Schulman, N. F.
Right arrow Articles by Vilkki, J. H.
J. Dairy Sci. 87:443-449
© American Dairy Science Association, 2004.

Quantitative Trait Loci for Health Traits in Finnish Ayrshire Cattle

N. F. Schulman1, S. M. Viitala1, D. J. de Koning2, J. Virta1, A. Mäki-Tanila1 and J. H. Vilkki1

1 MTT, Agrifood Research Finland, Animal Breeding, FIN-31600 Jokioinen, Finland
2 Department of Genetics and Biometry, Roslin Institute, Roslin, EH25 9P5 UK

Corresponding author: N. Schulman; e-mail: nina.schulman{at}mtt.fi.

A whole-genome scan was conducted to search for quantitative trait loci (QTL) affecting health traits in Finnish Ayrshire dairy cattle. The mapping population consisted of 12 bulls and their 491 sons in a granddaughter design. A total of 150 markers were typed covering all 29 autosomes. The traits under study were somatic cell score, mastitis, and a group of other veterinary treatments. Effects of the QTL and positions were estimated with the regression method. When carrying out interval mapping on each chromosome, cofactors were used to adjust for QTL identified at other chromosomes. Empirical P-values were obtained by permutation. Altogether 17 QTL were detected with genomewise significant P-values in the across family analysis. Quantitative trait loci affecting SCS were identified on chromosomes 1, 3, 11, 18, 21, 24, 27, 29, and QTL for mastitis on chromosomes 14, 18. Quantitative trait loci for other veterinary treatments were found on chromosomes 1, 2, 5, 8, 15, 22, and 23. The allele substitution effects were from 0.5 to 1.7 genetic standard deviations. The positions of these health QTL did not overlap with milk QTL detected in previous studies of the same population.

Key Words: QTL • health • mastitis • dairy cow

Abbreviation key: MAS = marker-assisted selection




This article has been cited by other articles:


Home page
J DAIRY SCIHome page
L. P. Sorensen, B. Guldbrandtsen, J. R. Thomasen, and M. S. Lund
Pathogen-Specific Effects of Quantitative Trait Loci Affecting Clinical Mastitis and Somatic Cell Count in Danish Holstein Cattle
J Dairy Sci, June 1, 2008; 91(6): 2493 - 2500.
[Abstract] [Full Text] [PDF]


Home page
Vet Rec.Home page
J. Conington, G. Cao, A. Stott, and L. Bunger
Breeding for resistance to mastitis in United Kingdom sheep, a review and economic appraisal
Vet Rec., March 22, 2008; 162(12): 369 - 376.
[Abstract] [Full Text] [PDF]


Home page
J DAIRY SCIHome page
M. S. Lund, G. Sahana, L. Andersson-Eklund, N. Hastings, A. Fernandez, N. Schulman, B. Thomsen, S. Viitala, J. L. Williams, A. Sabry, et al.
Joint Analysis of Quantitative Trait Loci for Clinical Mastitis and Somatic Cell Score on Five Chromosomes in Three Nordic Dairy Cattle Breeds
J Dairy Sci, November 1, 2007; 90(11): 5282 - 5290.
[Abstract] [Full Text] [PDF]


Home page
J DAIRY SCIHome page
B. S. Sharma, G. B. Jansen, N. A. Karrow, D. Kelton, and Z. Jiang
Detection and characterization of amplified fragment length polymorphism markers for clinical mastitis in canadian holsteins.
J Dairy Sci, September 1, 2006; 89(9): 3653 - 3663.
[Abstract] [Full Text] [PDF]


Home page
Biol. Reprod.Home page
S. Ponsuksili, R. M. Brunner, T. Goldammer, C. Kuhn, C. Walz, S. Chomdej, D. Tesfaye, K. Schellander, K. Wimmers, and M. Schwerin
Bovine NALP5, NALP8, and NALP9 Genes: Assignment to a QTL Region and the Expression in Adult Tissues, Oocytes, and Preimplantation Embryos
Biol Reprod, March 1, 2006; 74(3): 577 - 584.
[Abstract] [Full Text] [PDF]




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2004 by the American Dairy Science Association ®.