HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Risco, C. A. Articles by Thatcher, W. W. Search for Related Content PubMed PubMed Citation Articles by Risco, C. A. Articles by Thatcher, W. W.

Effects of Gossypol From Cottonseed on Hematological Responses and Plasma -Tocopherol Concentration of Dairy Cows

C. A. Risco^*, A. L Adams^,*,1, S. Seebohm^*, M.-J. Thatcher^*, C. R. Staples, H. H. Van Horn, L. R. McDowell, M. C. Calhoun and W. W. Thatcher

^* College of Veterinary Medicine and
Animal Sciences Department, University of Florida, Gainesville, FL 32611
Texas Agricultural Experimental Station. Texas AM University San Angelo, TX. 76901

Corresponding author:
C. A. R.; e-mail:
RiscoC{at}mail.vetmed.ufl.edu.

The effects of feeding whole cottonseed (WCS) and bovine somatotropin (bST) administration on hematological responses and plasma -tocopherol concentrations of lactating dairy cattle were examined. After parturition, multi and primiparous Holstein cows (n = 159) were assigned randomly to a 2 x 2 factorial arrangement of treatments consisting of (0 or 15% WCS and 0 or 208 mg of bST injected every 2 wk starting within 7 d after calving. Blood samples were collected from a subset group of 64 cows at 14, 28, 42, and 56 d postpartum. Blood was collected from all cows (n = 159) at 75, 96 and 120 d postpartum. Blood samples were analyzed for -tocopherol and total and (+)- and (–)-gossypol in plasma. Erythrocyte osmotic fragility, hemoglobin and hematocrit also were determined in blood. The mean concentrations of -Tocopherol, total, and (+) - and (–) - gossypol were higher in cows fed WCS regardless of bST administration and plateaued by d 75 postpartum. Hematocrit and hemoglobin concentrations were not affected by treatments. Erythrocyte osmotic fragility was higher in cows fed WCS, but the increase was attenuated when bST was injected (diet x bST interaction). No clinical signs of gossypol toxicity were observed in the cows consuming the WCS.

Abbreviation key: -T = -tocopherol, CSH = cottonseed hulls, EOF = erythrocyte osmotic fragility, WCS = whole cottonseed

Key Words: gossypol • whole cottonseed • bovine somatotropin • -tocopherol • erythrocytes • dairy cows

This article has been cited by other articles:

				J. E. P. Santos, H. Mena, J. T. Huber, and M. Tarazon Effects of Source of Gossypol and Supplemental Iron on Plasma Gossypol in Holstein Steers J Dairy Sci, October 1, 2005; 88(10): 3563 - 3574. [Abstract] [Full Text] [PDF]

				L. Xu, D. Yang, S. Wang, W. Tang, M. Liu, M. Davis, J. Chen, J. M. Rae, T. Lawrence, and M. E. Lippman (-)-Gossypol enhances response to radiation therapy and results in tumor regression of human prostate cancer Mol. Cancer Ther., February 1, 2005; 4(2): 197 - 205. [Abstract] [Full Text] [PDF]

				H. Mena, J. E. P. Santos, J. T. Huber, M. Tarazon, and M. C. Calhoun The Effects of Varying Gossypol Intake from Whole Cottonseed and Cottonseed Meal on Lactation and Blood Parameters in Lactating Dairy Cows J Dairy Sci, August 1, 2004; 87(8): 2506 - 2518. [Abstract] [Full Text] [PDF]