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* Department of Animal Science, Agricultural University of Norway, N-1432 Aas, Norway
Centre UdL-IRTA, Department of Animal Production, 25198 Lleida, Spain
Department of Morphology, Genetics and Aquatic Biology, The Norwegian School of Veterinary Science, N-0033 Oslo, Norway
Agricultural Research Centre MTT, Animal Production Research, 31600 Jokioinen, Finland
|| Chair of Animal Breeding, Technical University of Munich, D-85380 Freising-Weihenstephan, Germany
Corresponding author:
Hanne Gro Olsen; e-mail:
hanne-gro.olsen{at}ihf.nlh.no.
An autosomal genome scan for quantitative trait loci (QTL) affecting milk production traits was carried out on the Norwegian Dairy Cattle population. Six half-sibling families with a total of 285 sons organized according to a granddaughter design were analyzed by a multiple marker regression method. Suggestive QTL for one or several of the five milk traits (milk yield, protein percentage, protein yield, fat percentage and fat yield) were detected on chromosomes 3, 5, 6, 11, 13, 18 and 20. Among these results, the findings on chromosomes 3, 6, and 20 are highly supported by literature. The most convincing result was found close to marker FBN9 on chromosome 6, where a QTL was detected with alleles that cause a marked reduction in both protein and fat percentages and an increase in milk yield. The results for fat and protein percentage were highly significant even after accounting for multiple testing across the genome. Using bootstrapping, a 95% confidence interval for the position of the QTL for the percentage traits on chromosome 6 was estimated to 16 cM.
Key Words: quantitative trait loci • milk • cattle
Abbreviation key: BTA = bovine (Bos taurus) chromosome, CI = confidence interval, EBV = estimated breeding value, NCM = Norwegian Dairy Cattle Map
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