| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
1 Centre for Dairy Research, Department of Agriculture, The University of Reading, Earley Gate, Reading RG6 6AT England
Pancreatic and gut peptide hormones are potential mediators of the reduction in dry matter intake (DMI) often observed in lactating dairy cows fed supplemental fat. We investigated the effects of 7-d abomasal infusions of a rapeseed and sunflower oil mixture providing mostly unsaturated long-chain fatty acids (LCFA) on arterial concentration and splanchnic (portal-drained viscera [PDV] and liver) metabolism of insulin, pancreatic (PAN) and gut (GUT) glucagon, glucagon-like peptide-1 (7–36) amide (GLP-1), and cholecystokinin (CCK) in six cows at 55 (ELAC) and 111 (MLAC) d postpartum. Plasma flow for the PDV and liver were greater in ELAC and increased by oil infusion. Arterial concentrations of insulin and PAN were greater in MLAC, whereas arterial concentrations of GLP-1 and CCK were greater in ELAC. Abomasal oil infusion increased arterial concentration of GUT and GLP-1 but decreased arterial insulin concentration. These differences in peripheral hormone concentration were due largely to changes in their net PDV release and (or) liver removal. In addition, net liver removal of PAN was increased by oil infusion. There was no effect of oil infusion on splanchnic metabolism or arterial concentration of CCK. Lower concentrations of CCK in MLAC were attributable to net liver removal, emphasizing the importance of liver metabolism in determining peripheral concentrations of gut and pancreatic peptide hormones. Results of this study suggest a role for products of proglucagon processing (PAN, GUT, and GLP-1) as mediators of the reduction in DMI caused by postruminal supply of LCFA.
Key Words: gut hormones • insulin • glucagon • fat
Submitted on October 26, 2000
Accepted on February 8, 2001
This article has been cited by other articles:
|
|
 |
|
  B. J. Bradford, K. J. Harvatine, and M. S. Allen Dietary Unsaturated Fatty Acids Increase Plasma Glucagon-Like Peptide-1 and Cholecystokinin and May Decrease Premeal Ghrelin in Lactating Dairy Cows J Dairy Sci, April 1, 2008; 91(4): 1443 - 1450. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. A. Winkelman, T. H. Elsasser, and C. K. Reynolds Limit-Feeding a High-Energy Diet to Meet Energy Requirements in the Dry Period Alters Plasma Metabolite Concentrations but Does Not Affect Intake or Milk Production in Early Lactation J Dairy Sci, March 1, 2008; 91(3): 1067 - 1079. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. M. Hammon, C. C. Metges, P. Junghans, F. Becker, O. Bellmann, F. Schneider, G. Nurnberg, P. Dubreuil, and H. Lapierre Metabolic Changes and Net Portal Flux in Dairy Cows Fed a Ration Containing Rumen-Protected Fat as Compared to a Control Diet J Dairy Sci, January 1, 2008; 91(1): 208 - 217. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
U. Moallem, M. Katz, A. Arieli, and H. Lehrer Effects of Peripartum Propylene Glycol or Fats Differing in Fatty Acid Profiles on Feed Intake, Production, and Plasma Metabolites in Dairy Cows J Dairy Sci, August 1, 2007; 90(8): 3846 - 3856. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. N. Douglas, J. Rehage, A. D. Beaulieu, A. O. Bahaa, and J. K. Drackley Prepartum Nutrition Alters Fatty Acid Composition in Plasma, Adipose Tissue, and Liver Lipids of Periparturient Dairy Cows J Dairy Sci, June 1, 2007; 90(6): 2941 - 2959. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. E. Relling and C. K. Reynolds Feeding Rumen-Inert Fats Differing in Their Degree of Saturation Decreases Intake and Increases Plasma Concentrations of Gut Peptides in Lactating Dairy Cows J Dairy Sci, March 1, 2007; 90(3): 1506 - 1515. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. E. Relling and C. K. Reynolds Plasma Concentrations of Gut Peptides in Dairy Cattle Increase after Calving J Dairy Sci, January 1, 2007; 90(1): 325 - 330. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. J. Harvatine and M. S. Allen Effects of Fatty Acid supplements on feed intake, and feeding and chewing behavior of lactating dairy cows. J Dairy Sci, March 1, 2006; 89(3): 1104 - 1112. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. J. Harvatine and M. S. Allen The Effect of Production Level on Feed Intake, Milk Yield, and Endocrine Responses to Two Fatty Acid Supplements in Lactating Cows J Dairy Sci, November 1, 2005; 88(11): 4018 - 4027. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. B. Litherland, S. Thire, A. D. Beaulieu, C. K. Reynolds, J. A. Benson, and J. K. Drackley Dry Matter Intake is Decreased More by Abomasal Infusion of Unsaturated Free Fatty Acids than by Unsaturated Triglycerides J Dairy Sci, February 1, 2005; 88(2): 632 - 643. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. C. Swanson, J. A. Benson, J. C. Matthews, and D. L. Harmon Pancreatic exocrine secretion and plasma concentration of some gastrointestinal hormones in response to abomasal infusion of starch hydrolyzate and/or casein J Anim Sci, June 1, 2004; 82(6): 1781 - 1787. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. K. Reynolds, P. C. Aikman, B. Lupoli, D. J. Humphries, and D. E. Beever Splanchnic Metabolism of Dairy Cows During the Transition From Late Gestation Through Early Lactation J Dairy Sci, April 1, 2003; 86(4): 1201 - 1217. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. K. Drackley, T. M. Cicela, and D. W. LaCount Responses of Primiparous and Multiparous Holstein Cows to Additional Energy from Fat or Concentrate During Summer J Dairy Sci, April 1, 2003; 86(4): 1306 - 1314. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Benson, C. K. Reynolds, P. C. Aikman, B. Lupoli, and D. E. Beever Effects of Abomasal Vegetable Oil Infusion on Splanchnic Nutrient Metabolism in Lactating Dairy Cows J Dairy Sci, July 1, 2002; 85(7): 1804 - 1814. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
