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1 Department of Animal and Poultry Science, University of Guelph, Guelph, ON, Canada N1G 2W1
2 Department of Animal and Poultry Science, University of Guelph, Guelph, ON, Canada N1G 2W1 and Provel, Division Eli Lilly Canada Inc., Research Park Centre, Guelph, ON, Canada N1G 4T2
3 Provel, Division Eli Lilly Canada Inc., Research Park Centre, Guelph, ON, Canada N1G 4T2
Urinary 3 methyl-histidine excretion was measured in high yielding dairy cows between 10 and 3 d precalving and between 3 and 9 d postcalving. Cows received a sodium monensin controlled-release capsule or a placebo 3 wk before calving. Monensin did not affect urinary 3 methyl-histidine. Average urinary 3 methyl-histidine excretion was significantly higher postcalving (4.11 mmol d1) than precalving (2.48 mmol d1). This increase is assumed to be predominantly due to the negative nitrogen balance in the postcalving period caused by insufficient nutrient intake to meet nutrient requirements, which necessitates catabolism of mainly myofibrillar protein.
Key Words: 3 methyl-histidine transition myofibrillar protein monensin
Submitted on March 27, 2000
Accepted on July 18, 2000
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