-Tocopherol Concentrations in Milk and Plasma During Clinical Escherichia coli Mastitis

¹ Department of Dairy Science, The Ohio State University, Ohio Agricultural Research and Development Center, Wooster 44691
² Department of Veterinary Science, The Pennsylvania State University, University Park 16802
³ Hoffman-LaRoche Inc., Nutley, NJ 07110

Eighteen cows were challenged by intramammary infusion with Escherichia coli 727 to determine the effects of acute clinical mastitis on -tocopherol concentrations in plasma and milk. Cows were fed diets supplemented with 1000 IU of vitamin E/d from calving through the experimental period. At challenge, geometric mean DIM was 33 d. Each mammary quarter was diagnosed with an IMI and clinical mastitis at 24 and 48 h after challenge. The -tocopherol concentrations in milk from challenged quarters were approximately 60% greater by 24 and 48 h after challenge than concentrations at prechallenge and 168 h postchallenge. Plasma -tocopherol concentrations did not change after intramammary challenge. The -tocopherol in plasma and milk was correlated at 48 and 168 h postchallenge but at prechallenge or 24 h postchallenge. Milk -tocopherol and SCC were correlated positively across all sample periods. Milk fat and milk -tocopherol concentrations were correlated at each sample period except 24 h postchallenge. Increases in milk -tocopherol during clinical mastitis were not correlated to milk production, DMI, or BSA concentration in milk. Changes in milk -tocopherol concentration during clinical mastitis were similar to the dynamics of milk SCC.

Key Words: -tocopherol • mastitis Escherichia coli

Submitted on April 3, 1995
Accepted on August 31, 1995

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