JDS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Journal of Dairy Science Vol. 77 No. 7 1936-1951
© 1994 by American Dairy Science Association ®
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Horst, R. L.
Right arrow Articles by Reinhardt, T. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Horst, R. L.
Right arrow Articles by Reinhardt, T. A.

Calcium and Vitamin D Metabolism in the Dairy Cow

R. L. Horst 1, J. P. Goff 1, and T. A. Reinhardt 1

1 USDA, Agricultural Research Service, National Animal Disease Center, Metabolic Diseases and Immunology Research Unit, Ames, IA 50010-0070

Most dairy cows experience some degree of hypocalcemia during the periparturient period. There is, however, a subgroup of dairy cows that experience a breakdown in their ability to maintain plasma calcium and, consequently, suffer from severe hypocalcemia. This condition is also known as milk fever and usually occurs in cows in their third or greater lactation. The precise metabolic lesions responsible for the onset of milk fever have not yet been defined. Research has shown that milk fever is not the result of inadequate production of calcitropic hormones (parathyroid hormone and 1,25-dihydroxyvitamin D), but rather is more likely a result of inadequate receptor numbers or receptor dysfunction in the target cell of these hormones. This report reviews vitamin D and calcium metabolism, giving emphasis to 1,25-dihydroxyvitamin D receptor regulation and function as related to the periparturient dairy cow. The report also focuses on providing insights into nutritional (anionic diets) and endocrine strategies that have proved useful in milk fever management.

Key Words: calcium • vitamin D • parathyroid hormone • milk fever

Submitted on June 16, 1993
Accepted on October 15, 1993




This article has been cited by other articles:


Home page
 J DAIRY SCIHome page
B. J. Nonnecke, T. A. Reinhardt, and W. R. Waters
Short communication: The preruminant calf as a model for characterizing the effects of vitamin D status in the neonate
J Dairy Sci, November 1, 2009; 92(11): 5692 - 5696.
[Abstract] [Full Text] [PDF]

Home page
 J DAIRY SCIHome page
V. R. Moreira, L. K. Zeringue, C. C. Williams, C. Leonardi, and M. E. McCormick
Influence of calcium and phosphorus feeding on markers of bone metabolism in transition cows
J Dairy Sci, October 1, 2009; 92(10): 5189 - 5198.
[Abstract] [Full Text] [PDF]

Home page
 J DAIRY SCIHome page
M. S. Taylor, K. F. Knowlton, M. L. McGilliard, W. S. Swecker, J. D. Ferguson, Z. Wu, and M. D. Hanigan
Dietary calcium has little effect on mineral balance and bone mineral metabolism through twenty weeks of lactation in Holstein cows
J Dairy Sci, January 1, 2009; 92(1): 223 - 237.
[Abstract] [Full Text] [PDF]

Home page
 J DAIRY SCIHome page
V. S. Heron, G. F. Tremblay, and M. Oba
Timothy hays differing in dietary cation-anion difference affect the capability of dairy cows to maintain their calcium homeostasis
J Dairy Sci, January 1, 2009; 92(1): 238 - 246.
[Abstract] [Full Text] [PDF]

Home page
 Vet Rec.Home page
R. D. Murray, J. E. Horsfield, W. D. McCormick, H. J. Williams, and D. Ward
Historical and current perspectives on the treatment, control and pathogenesis of milk fever in dairy cattle
Vet Rec., November 8, 2008; 163(19): 561 - 565.
[Abstract] [Full Text] [PDF]

Home page
 J DAIRY SCIHome page
M. S. Taylor, K. F. Knowlton, M. L. McGilliard, W. M. Seymour, and J. H. Herbein
Blood Mineral, Hormone, and Osteocalcin Responses of Multiparous Jersey Cows to an Oral Dose of 25-Hydroxyvitamin D3 or Vitamin D3 Before Parturition
J Dairy Sci, June 1, 2008; 91(6): 2408 - 2416.
[Abstract] [Full Text] [PDF]

Home page
 J DAIRY SCIHome page
A. Liesegang
Influence of Anionic Salts on Bone Metabolism in Periparturient Dairy Goats and Sheep
J Dairy Sci, June 1, 2008; 91(6): 2449 - 2460.
[Abstract] [Full Text] [PDF]

Home page
 J ANIM SCIHome page
J. L. Montgomery, J. R. Blanton Jr., R. L. Horst, M. L. Galyean, K. J. Morrow Jr., D. B. Wester, and M. F. Miller
Effects of biological type of beef steers on vitamin D, calcium, and phosphorus status
J Anim Sci, July 1, 2004; 82(7): 2043 - 2049.
[Abstract] [Full Text] [PDF]

Home page
 J DAIRY SCIHome page
T. R. Overton and M. R. Waldron
Nutritional Management of Transition Dairy Cows: Strategies to Optimize Metabolic Health
J Dairy Sci, July 1, 2004; 87(13_suppl): E105 - 119.
[Abstract] [Full Text] [PDF]

Home page
 J DAIRY SCIHome page
M. R. Waldron, B. J. Nonnecke, T. Nishida, R. L. Horst, and T. R. Overton
Effect of Lipopolysaccharide Infusion on Serum Macromineral and Vitamin D Concentrations in Dairy Cows
J Dairy Sci, November 1, 2003; 86(11): 3440 - 3446.
[Abstract] [Full Text] [PDF]

Home page
 J DAIRY SCIHome page
T. Thilsing-Hansen, R. J. Jorgensen, J. M. D. Enemark, and T. Larsen
The Effect of Zeolite A Supplementation in the Dry Period on Periparturient Calcium, Phosphorus, and Magnesium Homeostasis
J Dairy Sci, July 1, 2002; 85(7): 1855 - 1862.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1994 by the American Dairy Science Association ®.