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Journal of Dairy Science Vol. 77 No. 2 462-467
© 1994 by American Dairy Science Association ®
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Therapy of Experimentally Induced Coliform Mastitis with a Propionibacterium acnes Product

J. S. Hogan 1, K. L. Smith 1, D. A. Todhunter 1, and P. S. Schoenberger 1

1 Department of Dairy Science, The Ohio State University, Ohio Agricultural Research and Development Center, Wooster 44691

The efficacy of a Propionibacterium acnes product for treatment of coliform mastitis was evaluated following intramammary infusion of Escherichia coli. Ten cows were injected intravenously with a product containing heat-killed P. acnes at 3 h, 3 d, and 7 d after bacterial challenge. Five cows served as untreated negative controls. Bacterial counts in milk, rectal temperatures, and milk SCC did not differ between treated cows and control cows. Intravenous infusion of P. acnes had no effect on milk production or DMI of treated cows compared with untreated controls. Therapy of experimentally induced coliform mastitis with a P. acnes product had no effect on severity or duration of clinical signs.

Key Words: coliform • mastitis • Propionibacterium acnes

Submitted on August 11, 1993
Accepted on October 7, 1993






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Copyright © 1994 by the American Dairy Science Association ®.