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Efficacy of Lasalocid and Decoquinate Against Coccidiosis in Naturally Infected Dairy Calves

Purdue University, West Lafayette, IN 47907

A 56-d growth study compared the effects of lasalocid and decoquinate, or a combination of the two, on rate of gain and control of naturally occurring coccidiosis in weaned Holstein calves. Sixty-four calves (mean BW of 188 kg; age 16 wk) were blocked by BW and degree of oocyst shedding and assigned randomly to one of four treatments with 4 calves per pen and 4 pens per treatment. Treatment groups included an unmedicated control group, lasalocid at 1 mg/kg of BW, decoquinate at .5 mg/kg of BW, or lasalocid plus decoquinate. For the combination treatment, decoquinate was fed at the recommended rate for 28 d, followed by lasalocid for the remaining 28 d of the study. Diets were based on dry-rolled corn and haylage and were fed once daily for ad libitum feed consumption. Calves were weighed weekly, and feces were collected for quantitation of oocyst shedding. Oocyst shedding was low, and clinical coccidiosis was not observed. However, unmedicated calves shed oocysts at a higher rate than medicated calves. Small differences were found among treatments on overall rate of gain and gain efficiency. There was little advantage in gain or performance when calves with subclinical coccidiosis were medicated with anticoccidial agents.