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Journal of Dairy Science Vol. 74 No. 1 328-339
© 1991 by American Dairy Science Association ®
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Cytokines: Applications in Domestic Food Animals

Frank Blecha 1

1 Department of Anatomy and Physiology, Kansas State University, Manhattan 66506

Cytokines such as human, bovine, and porcine interferons and human and bovine interleukin-1 and interleukin-2 have been used in vivo in cattle and pigs. Colony-stimulating factors and tumor necrosis factor alpha have been evaluated in vitro in food animals. Studies to evaluate cytokines in domestic food animals have munomodulation is possible in immunosuppressed or pathogen-exposed animals. Cytokine prophylaxis or therapy in food animals may have the greatest potential for control of respiratory disease and mastitis.

Key Words: cytokine • bovine • porcine

Submitted on September 18, 1989
Accepted on December 28, 1989






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Copyright © 1991 by the American Dairy Science Association ®.