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Journal of Dairy Science Vol. 73 No. 8 2157-2167
© 1990 by American Dairy Science Association ®
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Overall Efficacy of Chronically Administered Recombinant Bovine Somatotropin to Lactating Dairy Cows

J. H. Burton 1, G. K. MacLeod 1, B. W. McBride 1, J. L. Burton 1, K. Bateman 1, I. McMillan 1, and R. G. Eggert 1

1 Department of Animal and Poultry Science, University of Guelph, Guelph, Ontario, Canada N1G 2W1

Recombinant bST at daily dosages of 0, 10.3, 20.6, and 41.2 mg/d were injected for 266 d into 8, 10, 9, and 9 Holstein cows, respectively. Treatment effects of recombinant bST were assessed for milk production traits, BW, blood components, and health and reproductive variables. Data reported compare controls to all bST-treated cows. There was an average increase of 18% in 3.5% FCM for bST versus control cows. This increase resulted in enhand feed efficiency for bST cows, as their DM intakes were not elevated above those of the control cows. Recovery of BW was similar between control and bST groups. Milk composition was unaffected except for a slight decrease in protein percentage during the first 9 wk of treatment, and an elevated SCC between wk 19 and 28. Blood parameters were not different between control and bST cows, except for hematocrit, which decreased with bST treatment. The only health and reproductive parameters affected by bST were mastitis and days open, which were increased in the highest dosage groups.

Key Words: growth hormone • somatotropin • lactation • health • reproduction

Submitted on September 11, 1989
Accepted on February 20, 1990




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