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Journal of Dairy Science Vol. 72 No. 4 1045-1051
© 1989 by American Dairy Science Association ®
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Leukocytic Infiltration of Bovine Mammary Parenchymal Tissue in Response to Corynebacterium bovis Colonization

L. M. Sordillo1,2,, M. Z. Doymaz, S. P. Oliver and J. T. Dermody

Department of Animal Science, Institute of Agriculture, University of Tennessee, Knoxville 37901-1081

ABSTRACT

Morphological changes and local leukocyte response to prolonged Corynebacterium bovis colonization were studied in lactating bovine mammary glands. Morphometric analysis of parenchymal tissue demonstrated no adverse effects of colonization on the synthetic and secretory activity of mammary epithelium. Numbers of macrophages, lymphocytes, and plasma cells were higher in tissue from C. bovis-colonized quarters. However, there were no differences in numbers of neutrophils between colonized and uninfected quarters. Results suggest persistent C. bovis colonization may elicit effector cell populations in lactating mammary tissue where leukocyte concentrations tend to be lower.


FOOTNOTES

1 Current address: Veterinary Infectious Disease Organization, 124 Veterinary Road, University of Saskatchewan, Saskatoon, Saskatchewan, Canada S7N 0W0.

2 Send reprint requests to L. M. Sordillo.







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Copyright © 1989 by the American Dairy Science Association ®.