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Department of Animal Science, Institute of Agriculture, University of Tennessee, Knoxville 37901-1081
ABSTRACT
Morphological changes and local leukocyte response to prolonged Corynebacterium bovis colonization were studied in lactating bovine mammary glands. Morphometric analysis of parenchymal tissue demonstrated no adverse effects of colonization on the synthetic and secretory activity of mammary epithelium. Numbers of macrophages, lymphocytes, and plasma cells were higher in tissue from C. bovis-colonized quarters. However, there were no differences in numbers of neutrophils between colonized and uninfected quarters. Results suggest persistent C. bovis colonization may elicit effector cell populations in lactating mammary tissue where leukocyte concentrations tend to be lower.
1 Current address: Veterinary Infectious Disease Organization, 124 Veterinary Road, University of Saskatchewan, Saskatoon, Saskatchewan, Canada S7N 0W0.
2 Send reprint requests to L. M. Sordillo.
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