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Vaccines against Endogenous Hormones: A Possible Future Tool in Animal Production¹

Washington State University, Pullman 99164

ABSTRACT

Vaccines have been widely used by the livestock industry to control and prevent disease. New technologies now permit development of vaccines against hormones that control reproduction, growth, and lactation in domestic farm animals. Results of research projects studying passive and active immunization against such hormones as estrogen, testosterone, LH, FSH, and somatotropin have demonstrated that reproductive efficiencies and growth can be altered through vaccination. Although immunizations against most of the hormones studied have proven effective in most cases, there remain problems related to longevity, consistency, and efficiency of response both within and between animals. When these areas have been clearly defined for individual hormones, standardized immunization regimens can be developed mat will optimize antibody production in the animal, thus providing the animal agriculture industry with a powerful and profitable production tool.

¹ Supported by Project 0137, College of Agriculture. The authors would like to thank Sylvia Becker for her editorial assistance in writing this review.

² Department of Animal Sciences.

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