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Orotic Acid in Guinea Pig Milk: Changes in Concentration During Lactation¹

Department of Dairy Science, University of Missouri-Columbia, Columbia 65211

ABSTRACT

The orotic acid concentration in guinea pig milk decreased rectilinearly beginning on d 1 through a lactation duration of 21 d. Concentration was 29 µg/ml on d 1 and 5 µg/ml on d 17. On d 18 to 21 it was less than 1 µg/ml. The regression equation of orotic acid on day of lactation was: Y(micrograms orotic acid per milliliter milk) equals 32.3 –1.6x (day of lactation) with a correlation coefficient of .94. Total orotic acid on a daily basis peaked on d 6 at 950 µg and declined to less than 5 µg by d 21. The rectilinear regression equation from d 6 to 21 was as follows: Y(micrograms orotic acid per milliliter milk) equals –1.64 + .68x (grams of milk production per day) with a correlation coefficient of .97. This may be used as a marker for persistency of lactation.

¹ Contribution from the Missouri Agricultural Experiment Station, Journal Series 10453. Approved by the Director.