HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Neathery, M. W. Articles by Blackmon, D. M. Search for Related Content PubMed PubMed Citation Articles by Neathery, M. W. Articles by Blackmon, D. M.

Influence of High Dietary Lead on Selenium Metabolism in Dairy Calves^{1, 2,}

Departments of Animal and Dairy Science University of Georgia, Athens 30602

ABSTRACT

Metabolism of orally dosed ⁷⁵Se was studied in 10 intact male Holstein calves that were fed ad libitum a control diet containing no added Pb or supplemented with 1000 ppm Pb as PbSO₄ for 4 wk. Lead-supplemented calves did not exhibit any clinical signs of Pb toxicity. Voluntary feed intake was reduced by 9.5% and average daily gain by 23%. Lead content of rib, liver, and kidney increased. Serum glutamic oxaloacetate transaminase activity was increased during the last 2 wk of the experiment in calves fed Pb.

In calves receiving supplemental Pb, ⁷⁵Se absorption, blood concentration, and urine concentration were reduced by 26, 21, and 42%, respectively. Tissue ⁷⁵Se concentrations were significantly lower in kidney, liver, testicle, pancreas, small intestine, heart, spinal cord, and muscle in calves fed Pb. There was a significant negative correlation (r = –.78) between ⁷⁵Se and stable Pb concentrations in the liver. It is not clear whether the ingestion of subclinical amounts of Pb could affect the absorption and utilization of Se in dairy calves to the extent of Se deficiency when dairy calves are kept in areas known to be low in Se.

¹ Supported by state and Hatch funds allocated to the Georgia Agricultural Experiment Stations.

² Department of Animal and Dairy Science.

³ Department of Large Animal Medicine.