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Vitamin D Metabolism in Ruminants and Its Relevance to the Periparturient Cow

National Animal Disease Center, ARS, USDA, P. O. Box 70, Ames, IA 50010

ABSTRACT

Complexity of vitamin D metabolism and its interaction with calcium-regulating hormones in ruminants have received little attention. Data of this report focus on the uniqueness of the bovine in its metabolism of vitamin D. Also, control of vitamin D metabolism in the periparturient cow and the ultimate mode of action of the steroid hormone 1,25-dihydroxyvitamin D at its target tissues relative to the onset of parturient paresis are reviewed.

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