HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Ishikawa, H. Articles by Nakano, T. Search for Related Content PubMed PubMed Citation Articles by Ishikawa, H. Articles by Nakano, T.

Protein Composition of Whey from Subclinical Mastitis and Effect of Treatment with Levamisole

Hokkaido Branch Laboratory, National Institute of Animal Health, Hitsujigaoka 4, Sapporo 061-01, Japan

H. Hirano, N. Saito and T. Nakano

Niikappu Livestock Breeding Station, Shizunai, Hokkaido 056-01, Japan

ABSTRACT

Subclinical mastitis caused a rise in the noncasein protein concentration of milk. This mainly was caused by an increase in the concentration of serum albumin and immunoglobulin derived from blood. In most cases, the concentration of the major whey proteins ß-lactoglobulin and -lactalbumin decreased. This decrease can be attributed to both inflammatory damage of mammary secretory tissues and destruction of blood-milk permeability barriers. When used orally, levamisole reduced leukocyte count and intramammary pathogens. Although changes of concentration were least for relative amounts of ß-lactoglobulin, serum albumin, and immunoglobulin, we observed enhanced -lactalbumin production and simultaneous reduction of the total whey protein as mastitis score decreased. In normal quarter milk, the relative amount of immunoglobulin increased with levamisole. This suggests there was increased transport of immunoglobulin to aid udder health.