JDS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Journal of Dairy Science Vol. 64 No. 3 526-532
© 1981 by American Dairy Science Association ®
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Grummer, M. A.
Right arrow Articles by Larson, B. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Grummer, M. A.
Right arrow Articles by Larson, B. L.

Subcellular Localization of Pyrimidine Synthesis Enzymes in Bovine Mammary Tissue1

M. A. Grummer1 and B. L. Larson

Department of Dairy Science, University of Illinois, Urbana 61801

ABSTRACT

Subcellular localization of enzymes of the pyrimidine biosynthetic pathway was determined in lactating bovine mammary tissue. Aspartate transcarbamylase was associated with a membrane portion of the microsomal cell fraction. Dihydroorotate dehydrogenase was in the mitochondrial fraction with no evidence for a cytosolic enzyme requiring pyridine nucleotides. Orotate phosphoribosyltransferase was in the cytosol of the cell. The significance of these findings to other mammalian cells and orotic acid accumulation in bovine milk is discussed.

FOOTNOTES

1 Taken from M.S. thesis of M. A. Grummer. Supported by a Grant-in-Aid from the National Dairy Council and Hatch Project 35-351 of the Illinois Agricultural Experiment Station.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1981 by the American Dairy Science Association ®.