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Department of Animal Science, Cornell University, Ithaca, NY 14853
1 Address reprint requests to this author.
ABSTRACT
Four cows with exteriorized carotid arteries were in an intensive study of concentrations in plasma and mammary extraction of propionate. A restricted-roughage, high-grain diet produced higher arterial propionate concentrations and larger carotid-subcutaneous abdominal vein (arteriovenous) differences than the control diet. Concomitant changes in acetate, ß-hydroxybutyrate, and glucose in plasma and in fat and protein in milk were measured. Mammary arteriovenous difference in propionate was correlated negatively with milk fat percentage. However, since arterial propionate and ß-hydroxybutyrate also were correlated negatively, evidence of a direct inhibitory effect of propionate in mammary gland is equivocal.
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