JDS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Journal of Dairy Science Vol. 62 No. 9 1415-1419
© 1979 by American Dairy Science Association ®
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Jaimes, R. E.
Right arrow Articles by McGilliard, M. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Jaimes, R. E.
Right arrow Articles by McGilliard, M. L.

Distributional Uptake of {gamma}-Globulin in Small Intestine of Neonatal Calves

R. E. Jaimes1, C. E. Polan and M. L. McGilliard

Department of Dairy Science, Virginia Polytechnic Institute and State University, Blackburg 24061

ABSTRACT

Abstarct: Newborn calves deprived of colostrum were used to determine distribution of uptake of {gamma}-globulin labeled with iodine-125 in small intestine. Ten calves less than 12.5 h of age (average 7 h) were anesthetized, and intestines were exteriorized through an abdominal incision. Intestine was ligated into 10-cm segments, 70 cm apart, beginning at the ileocecal junction and progressing anteriorally, then each segment injected with 100 mg ({acd} 1 µCi) labeled {gamma}-globulin in 5 ml electrolyte solution, and incubated for 1.5 h. One additional segment was formed adjacent to segments 1,5, and 10 to assess uptake after .5 h incubation with [iodine-125] {gamma}-globulin. After prescribed {gamma}-globulin exposure, segments were excised; then volume of lumen contents, segment weight, and tissue activity were measured. The location of each segment was the percentage of distance from cecum to abomasum. Uptake was milligrams {gamma}-globulin per gram of segment tissue. Distribution of {gamma}-globulin uptake after 1.5 h incubation was a cubic function of segment position. Uptake was greatest in a region 15% of the cecum-abomasum distance and declined progressively toward the abomasum. After .5-h incubation with {gamma}-globulin, regression of uptake on segment position was a quadratic function with greatest uptake at 30% of cecum-abomasum distance. Uptake was greater in segments exposed to {gamma}-globulin for 1.5 h than .5 h.

FOOTNOTES

1 New England Nuclear, Boston, MA 02118.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1979 by the American Dairy Science Association ®.