HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Paape, M. J. Articles by Pearson, R. E. Search for Related Content PubMed PubMed Citation Articles by Paape, M. J. Articles by Pearson, R. E.

Leukocytes—Second Line of Defense Against Invading Mastitis Pathogens

U.S. Department of Agriculture, Science and Education Administration, Animal Physiology and Genetics Institute, Beltsville, MD 20705

ABSTRACT

In mammals, neutrophile polymorphonuclear leukocytes constitute one of the essential body defenses against disease. In a large mammal, such as the dairy cow, billions of neutrophils are mobilized to fight infection. For example, over 50 million neutrophils per milliliter milk are commonly in a mammary quarter inflicted with clinical mastitis. However, in spite of these numerous leukocytes, pathogenic organisms remain viable. Recent evidence indicates that bacteria are not eliminated from a diseased quarter because the phagocytic capacity of the neutrophils is reduced in the mammary gland. The morphology and physiology of the leukocyte is examined in this review in an attempt to explain why the phagocytic capacity of the neutrophil is reduced in the mammary gland of the bovine.

This article has been cited by other articles:

				W. P. Weiss and J. S. Hogan Effects of Dietary Vitamin C on Neutrophil Function and Responses to Intramammary Infusion of Lipopolysaccharide in Periparturient Dairy Cows J Dairy Sci, February 1, 2007; 90(2): 731 - 739. [Abstract] [Full Text] [PDF]

				P. Boutet, F. Bureau, G. Degand, and P. Lekeux Imbalance Between Lipoxin A4 and Leukotriene B4 in Chronic Mastitis-Affected Cows J Dairy Sci, November 1, 2003; 86(11): 3430 - 3439. [Abstract] [Full Text] [PDF]