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Isolation and Characterization of Nonesterified 3-Hydroxy Acids in Milk

Eastern Regional Research Center¹, Philadelphia, PA 19118

ABSTRACT

Nonesterified 3-hydroxy acids of unknown origin, ranging in chain length from 6 to 16 carbons are identified in milk. Content of 3-hydroxydecanoic acid is estimated at 25 to 50 µg per liter of milk. It is proposed that the 3-hydroxy acids originate in milk as side products of fatty acid synthesis by way of the Malonyl CoA pathway rather than as fatty acid degradation products.

¹ Agricultural Research Service, U.S. Department of Agriculture.

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