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Journal of Dairy Science Vol. 59 No. 9 1599-1602
© 1976 by American Dairy Science Association ®
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Effect of Glucagon Infusion on Plasma Magnesium, Glucose, and Insulin in Bull Calves1

F. C. Madsen2, D. E. Lentz, J. K. Miller and S. L. Hansard

Comparative Animal Research Laboratory, Oak Ridge, TN 37830

ABSTRACT

Two Holstein bull calves each were infused intravenously with 1 mg glucagon in .9% sodium chloride, and two were given saline alone; 1 wk later treatments were reversed. Glucagon increased concentrations of insulin and glucose but decreased potassium in blood plasma and moderately increased urinary magnesium and calcium losses. When only saline was used, there was no effect. A hypothesis relating elevated glucagon to grass tetany is proposed.

FOOTNOTES

1 Research at the Comparative Animal Research Laboratory operated by the University of Tennessee for the US Energy Research and Development Administration under Contract No. E-40-1-GEN-242. Supported by the US Department of Agriculture and the University of Tennessee Agricultural Experiment Station.

2 Syntex Agri Business, Inc., Springfield, MO 65805.






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Copyright © 1976 by the American Dairy Science Association ®.