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Formation and Role of Unusual Whey Proteins and Enzymes: Relation to Mammary function^{1 ,2,}

Department of Dairy Science, Ohio Agricultural Research and Development Center, Wooster 44691

ABSTRACT

Introduction

Previous studies of mammary gland function and control have dealt with either gross milk composition or changes in tissue metabolites, enzymes, or histology. Relatively little attention has been given to protein composition of mammary secretions other than normal milk. We are thus limited in our further attempts to understand the different states of mammary function because we have little knowledge of what proteins or enzymes are in the different mammary secretions and, hence, what functional capacity the gland might have beyond normal milk secretion. Similarly, we are also limited in our understanding of the roles of the various whey proteins and enzymes since for most we have little indication of their concentrations and relative importance in mammary secretions other than normal milk.

The mammary gland is a highly integrated and complex organ. Further, it is readily able to change functional capacity, either autonomously or via hormone mediation or disease.

¹ Journal Article 76–74, Ohio Agricultural Research and Development Center, Wooster 44691.

² Partially supported by the Herman A. Frasch Foundation.

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