HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Young, J. W. Articles by McGilliard, A. D. Search for Related Content PubMed PubMed Citation Articles by Young, J. W. Articles by McGilliard, A. D.

Effects of Phlorizin on Glucose Kinetics in the Bovine¹

Department of Animal Science, Iowa State University, Ames 50010

ABSTRACT

Glucose excretion from phlorizin was established in calves given different diets and/or different phlorizin doses; the ability of phlorizin to alter gluconeogenesis then was investigated. In calves fed hay, maximum glucose excretion of up to 313 g/day was caused by about 2 g of phlorizin per day. When calves were given only single doses of phlorizin subcutaneously, there was an increased glucose excretion with each increase in phlorizin up to 2 g with either a hay or a grain diet. At all phlorizin dosages, calves fed a high-grain diet had over two times greater glucose excretion than those fed hay. In three grain-fed calves where phlorizin caused an average glucose excretion of 360 g/day, the only parameter of glucose kinetics that changed from control calves not given phlorizin was irreversible loss, which increased 8.2 g/h. Neither pool size nor total entry rate was affected. Phlorizin did not increase gluconeogenesis in fed ruminants.

¹ Journal Paper J-7767, ofthe Iowa Agriculture and Home Economics Experiment Station, Ames, Iowa. Project No. 1910. Supported in part by funds provided by Grant AM-10706, Department of Health, Education and Welfare.