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Metabolic Effects in Lambs Intravenously Infused with Xylitol, Medium Chain Triglycerides, and Corn Oil¹

Department of Animal Husbandry, University of Missouri, Columbia 65201

ABSTRACT

Our experiment determined if xylitol, corn oil, and medium chain triglycerides administered by intravenous infusion could serve as useful metabolic fuels for supporting nitrogen balance in ruminants with the lamb as the model. Xylitol at 400 kcal per day was well tolerated; it decreased urinary and fecal nitrogen and increased nitrogen balance. Xylitol infusion consistently lowered blood glucose by 20 mg/100 ml and reduced plasma urea nitrogen. Medium chain triglycerides and corn oil increased plasma urea nitrogen and the respiratory rate. The reduction in blood glucose, after medium chain triglycerides infusion averaging 10 mg/100 ml from the control, was inconsistent and variable. No significant reduction in blood glucose occurred after intravenous infusion of corn oil.

¹ Contribution from the Missouri Agricultural Experiment Station Journal Series No. 7141. Approved by the Director. This work was partially supported by a grant from Masonite Corporation, Chicago, Illinois.

² Current address: Agricultural College of Norway, 1432 Vollebekk, Norway.