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Variations in the Electrophoretic Distribution of Low Density Lipoproteins of Holstein Cows^1,2,

Lipids Laboratory, The Pennsylvania State University, University Park 16802

ABSTRACT

The properties of serum lipoproteins during various stages of gestation and lactation of Holstein cows are being characterized. This paper reports changes in the electrophoretic distribution of serum low density lipoproteins. Electrophoretic -lipoproteins normally can be isolated ultracentrifugally in the high density lipoprotein class of most mammals, but in certain cases -lipoproteins have been isolated in the low density lipoprotein class as well. Low density -lipoproteins of Holstein cows have been observed to increase during lactation. The possible relationship between these -lipoproteins and very low density lipoprotein metabolism is discussed.

¹ Authorized for publication on August 5, 1971 as Paper 4036 in the Journal Series of the Pennsylvania Agricultural Experiment Station.

² Supported in part by the Pennsylvania Department of Agriculture and Kesearch Grant HE 03632 of the U.S. Public Health Service.