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Effect of Methane Inhibitors on Rumen Metabolism and Feedlot Performance of Sheep

Applebrook Animal Health Research Center, Smith Kline & French Laboratories, 1600 Paoli Pike, West Chester, Pennsylvania 19380

ABSTRACT

In vitro and in vivo rumen fermentation studies and a lamb performance trial were conducted to discover and evaluate the effect of methane formation-suppressing compounds on rumen metabolism and performance. These experiments indicate that methane inhibitors significantly alter ruminal metabolism resulting in a potentially favorable shift in the proportions of useful metabolites produced in the rumen. The performance data with lambs indicate a trend toward improved feed efficiency with the inhibitor.