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Alterations in Blood and Milk Lipids Produced by Administration of Triton WR-1339

Animal Science Research Division, RS, USDA, Beltsville, Maryland 20705

ABSTRACT

Attempts have been made to increase milk fats by increasing blood lipids with the surface active detergent, Triton WR-1339. In experiments with lactating rats, feeding a 3% Triton diet did not consistently increase milk or blood cholesterol and triglycerides. A 200-mg dose given intravenously caused hyperlipemia, but no consistent results were obtained for milk lipids.

Dairy cows given intravenous infusions (125 to 500 mg/kg body weight) of Triton responded with elevated blood lipids. Triglycerides in blood increased about 15-fold, and cholesterol tripled. The blood lipid response was slower in cows than in rats. Lipid content of milk was not significantly affected by the treatment, even at time of highest blood levels. Reduction in feed intake and milk production of cows occurred. The higher levels of Triton administration were accompanied by edema of the brisket which persisted for 2 to 4 days.