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Journal of Dairy Science Vol. 52 No. 9 1384-1387
© 1969 by American Dairy Science Association ®
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Oral Administration of Supracide to Lactating Cows: Effect on Consumption, Production, Ration Utilization, and Residue Levels in Milk and Certain Tissues

Carl E. Polan, J. T. Huber1, C. N. Miller and R. A. Sandy

Dairy Science Department Virginia Polytechnic Institute, Blacksburg 24061

ABSTRACT

In two experiments, thirty-two cows and four steers were utilized to study the effect of oral administration of Supracide, a new organophosphate insecticide. In Experiment 1, Supracide was given by capsule twice daily at levels of 30, 15, 7.5, and zero ppm of the total air dry feed consumed. Level of treatment had no observed effect on voluntary hay or total feed consumption, milk production, blood cholinesterase, or transaminase activity, nor or digestibility of proximate components. In a balance trial, neither Supracide nor its oxygen analogue was detected in the milk, urine, or feces at a sensitivity of 0.005 and 0.025 ppm, respectively. Analysis of several tissue samples from a cow and steer at the two highest treatments revealed no pesticide residues. In Experiment 2, hay harvested the day following field treatment with GS-13005 at twice an effective control level was fed to cows at three levels of intake beginning seven days after cutting and continued for 35 days. Neither voluntary intake nor production was affected. Milk sampled on Day 35 of treatment did not contain Supracide nor its oxygen analogue.

FOOTNOTES

1 Present address: Michigan State University, Department of Dairy Science, East Lansing, Michigan 48823.






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Copyright © 1969 by the American Dairy Science Association ®.