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Efficacy of Staphylococcal Vaccines to Elicit Antistaphylococcal Alpha-Hemolysin in Dairy Cows

Department of Dairying, Tennessee Agricultural Experiment Station, Knoxville

ABSTRACT

Five staphylococcal vaccines containing standardized bacterin and toxoid but different adjuvants were prepared to determine the efficacy in eliciting antistaphylococcal alpha-hemolysin in dairy cows. The vaccine containing Freund's complete adjuvant was clearly the most efficacious. There were no significant differences among efficacies of vaccines containing either no adjuvant, alum, Freund's incomplete adjuvant, or sodium alginate.

¹ Department of Biology, Western Kentucky University, Bowling Green, Kentucky 42101.

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