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Metabolism of 3,3'-Dichloro-5,5'-Dinitro-0,0'-Biphenol (Bayer 9015) Anti-Fluke Agent in a Lactating Cow

Pesticide Residue Laboratory Department of Entomology Cornell University, Ithaca, New York

ABSTRACT

The metabolism of Chemagro Corporation's anti-fluke agent, Bayer 9015 (3,3'-dichloro-5,5'-dinitro-0,0'-biphenol), has been studied in a lactating cow. No residues were detected in milk or urine up to nine days after oral administration of a single dose of 3 mg/kg of the compound to a 635-kg Holstein cow. A trace (0.17 ppm) of the intact compound was found in the feces about two days after dosing. The compound disappeared within six minutes when incubated at a concentration of 5 ppm with fresh rumen fluid.