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Postpartum Changes in Milk Serum Protein Fractions

Department of Dairy Science, Ohio Agricultural Research and Development Center, Wooster

ABSTRACT

Polyacrylamide gel disc electrophoresis was used to study changes in the relative concentration of the ß-lactoglobulin, - lactalbumin, blood serum albumin, and immune globulin in milk serum during the first 21 days post-partum. All four protein fractions were found to be concentrated in colostrum serum at parturition, with immune globulin being a major fraction. A graphic analysis of the change in the total protein of the four fractions studied indicates that this change behaves as a biphasic process. The first phase, a simple dilution effect, lasts approximately 60 hr. In ten days a fairly stable relationship is established between the relative concentration of the four protein fractions of milk serum, with ß-lactoglobulin being the major fraction.