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Contribution of Blood Typing to Dairy Science Progress

Serology Laboratory, University of California, Davis

ABSTRACT

I have been invited to tell you about the contribution of blood typing to dairy science progress. In his invitational letter, C. L. Norton suggested that a brief review of blood typing procedures would be very much in order.

Blood typing refers to the testing of the red blood cells of an individual with a selected battery of antibody fluids, often referred to as reagents. Such reagents are generally designated anti-A, anti-B, anti-C, . . . etc., where the letters A, B, C, . . . etc., represent specifically different antigenic specificities (blood factors) or antibody-combining sites on the surface of the red cell.

When the antibodies in a blood-typing reagent are specifically bound by the red cells, two kinds of reactions will usually ensue. One of these is agglutination, merely a clumping of the red cells. The other is hemolysis; but hemolysis will not ensue unless an enzyme-like component known as complement is supplied to the mixture of red cells and antibodies.

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