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Department of Dairy Science, University of Illinois, Urbana
ABSTRACT
Studies with human blood have shown that acetate-1-C14 is incorporated into lipids and that leukocytes and platelets are primarily responsible for the synthesis (4, 5, 7, 8, 12). Formation of fatty acids by leukocytes accounts for approximately two-thirds of the C14 incorporation (5, 8, 12). Fatty acid synthesis by erythrocytes is very limited and appears to occur only in immature cells (8, 10, 11). Marks et al. (8) found that about two-thirds of the incorporation of acetate-1-C14 by leukocytes of human blood was into neutral lipids and about one-third into phospholipds. Platelets had an incorporation ratio of about 60:40 into neutral and phospholipids, respectively. The greatest per cent of acetate-1-C14 activity resided in the long-chain fatty acid fraction (5, 10). Garton (4) concluded that palmitic acid is the major higher fatty acid formed from the acetate by blood. No similar studies with ruminant blood are known to the authors.
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