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Effect of Antibiotic Administration on Mastitis Screening Tests and Milk Composition¹

Departments of Dairy Science and Veterinary Science, University of Wisconsin, Madison

ABSTRACT

Intramammary infusion of a commercial antibiotic mixture or aqueous penicillin resulted in a marked inflammatory reaction characterized by increases in leucocyte numbers and degree of reaction to mastitis screening tests. Milk lactose content was decreased significantly. Penicillin infusion resulted in an apparent decrease in streptococcus organisms, but had little effect on staphylococci.

Intramuscular injection of streptomycin had only minor effects on leucocytes, screening tests, milk composition, or bacteriological status of the individual quarters.

Intramuscular penicillin injection resulted in significant decreases in leucocytes and reactions to the mastitis screening tests. Protein and lactose content of the milk were increased. There was a reduction in the number of quarters shedding staphylococcus as well as streptococcus organisms.

¹ Published with the approval of the Director of the Wisconsin Agricultural Experiment Station.