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Journal of Dairy Science Vol. 49 No. 3 312-314
© 1966 by American Dairy Science Association ®
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Inactivation of Nisin by Pancreatin

B. Heinemann and R. Williams

Producers Creamery Company, Springfield, Missouri

ABSTRACT

Nisin is readily inactivated by pancreatin at pH 8.0 when held at 37 C for 15 to 30 min. It is reasonable to expect, therefore, that nisin cannot influence the intestinal flora. Bacitracin, tetracycline, oxytetracycline, chlortetracycline, penicillin, and tylosin were medical antibiotics used to influence the intestinal flora. These were all found to be stable under the same digestion conditions which rapidly inactivated nisin.






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Copyright © 1966 by the American Dairy Science Association ®.