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Department of Bionucleonics and Animal Sciences, Purdue University, West Lafayette, Indiana
ABSTRACT
The effect of the administration of carrier iodine prior to and after the administration of radioactive iodine upon the whole body retention of Iodine-131 in calves was studied. The technique of whole body liquid scintillation counting was employed to follow Iodine-131 retention. Four young male calves were dosed with Iodine-131 and the whole body Iodine-131 retention determined with time. After the total body radioactivity was back to essentially background levels, the experiment was repeated, except stable iodine (as potassium iodide) was administered for a period of 12 days preceding and following the administration of Iodine-131. Previous administration of carrier iodine, in the form of potassium iodide, to calves decreased the whole body retention of subsequently administered Iodine-131 by approximately one-half after 23 days.
1 This investigation was supported in part by a U.S. Public Health Service Predoctoral Fellowship and the Medical Research Branch, Division of Biology and Medicine, Atomic Energy Commission, under Contract no. AT(11-1)-876.
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