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Sites of Gastrointestinal-Blood Passage of Iodide and Thyroxine in Young Cattle¹

Agricultural Research Laboratory of the University of Tennessee, Oak Ridge, Tennessee³

ABSTRACT

A nonabsorbed marker technique (Ce¹⁴⁴) has been used to determine the net absorption and endogenous secretion of orally administered radioiodide in young animals. The rumen appears to be a major site of absorption and the abomasum a major site of endogenous secretion. Net absorption occurred from the second section of the small intestine throughout the remainder of the tract. Following intravenous administration of labelled NaI one-half hour prior to slaughter, a significantly greater concentration of radioactivity was found in the abomasum than in the first part of the small intestine. The reverse was true for iodine from 1-thyroxine.

¹ This manuscript is published with the permission of the Director of the University of Tennessee Agricultural Experiment Station, Knoxville.

² Fulbright and Smith-Mundt Fellow-Professor, Veterinary School, San Marcos University, Lima, Peru.

³ Operated by the Tennessee Agricultural Experiment Station for the United States Atomic Energy Commission under Contract No. AT-40-1-GEN-242.