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Depression of Milk Secretion during Insulin Administration¹

School of Veterinary Medicine, University of Pennsylvania, Kennett Square

ABSTRACT

Long-acting insulin was injected intramuscularly twice a day into two cows. Their daily milk yield and plasma glucose concentration both decreased. Glucose was then infused intravenously while the insulin injections were continuing. When the plasma glucose was restored to a normal level, the milk secretion returned to the pretreatment rate. These observations suggest that hypoglycemia is a more direct cause of hypogalactia than is insulin.

¹ This work was supported by the U. S. Public Health Service, Grant AM-04927 of the National Institute of Arthritis and Metabolic Disease, and Dr. Mayer is a post-doctoral fellow, APD-14, 874.

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