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Chemical State and Nutritional Availability of Iron in a Prepared Infant Formula

Ross Laboratories, Columbus, Ohio

ABSTRACT

The distribution and chemical state of ferrous iron added to a prepared infant formula was studied, using Fe⁵⁹ as a tracer. The iron was found to be almost entirely associated with the milk proteins. Before protein hydrolysis, only 3% of the iron was dialyzable against either distilled water or a citrate solution, but after hydrolysis in vitro, 20% of the iron was dialyzable against water and 79% against citrate solution. Digestion in vivo increased the percentage of dialyzable iron still further. Most of the iron added to milk products exists as a soluble protein iron complex and it is available nutritionally after the protein portion of the complex is digested.

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