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Journal of Dairy Science Vol. 43 No. 4 553-562
© 1960 by American Dairy Science Association ®
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Studies on 9{alpha}-Fluoroprednisolone Acetate, A New Synthetic Corticosteroid for the Treatment of Bovine Ketosis

A. W. Neff, N. D. Connor and H. S. Bryan

Veterinary Division, The Upjohn Company, Kalamazoo, Michigan

ABSTRACT

A new synthetic corticosteroid, 9{alpha}-fluoroprednisolone acetate, Predef ®1, has been shown to be approximately ten times as potent as prednisolone in its ability to elevate blood glucose in normal lactating dairy cows. Blood mineral studies demonstrated the influence of 9{alpha}-fluoroprednisolone acetate on phosphorus, sodium, potassium, calcium, and magnesium. 9{alpha}-fluoroprednisolone acetate is indicated in the treatment of bovine ketosis.






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Copyright © 1960 by the American Dairy Science Association ®.