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Effects of Isoniazid and Chlortetracycline in the Diet of Young Calves ¹

Department of Dairy Science, University of Florida, Gainesville

ABSTRACT

Under most conditions chlortetracycline stimulates growth and efficiency of feed conversion in young calves, possibly by control of subclinical infections (3). Isoniazid enhances the effect of streptomycin on pathogenic organisms (1). The present work was undertaken to determine if isoniazid and chlortetracycline are synergistic or additive in promoting well-being, as reflected by growth and efficiency of feed conversion in young calves.

New-born calves were allocated to four dietary groups on the basis of body weight, height at withers, breed, and sex. Each group consisted of three Guernseys (two males and one female), seven Jerseys (four males and three females), and one Holstein female.

Experimental subjects were removed from their dams after nursing once. They were confined to individual pens and offered chopped alyceclover hay, and dry mixed concentrates, free choice. The concentrate mixture consisted of: ground shelled corn, 300 parts; ground oats, 250 parts; wheat bran, 100 parts; cottonseed meal (41% protein), 130 parts; nonfat dry milk solids, 100 parts; common salt, 8.5 parts; and steamed bonemeal, 17 parts.

¹ Florida Agricultural Experiment Station Journal Series, No. 596.