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Observations on the Infusion of Penicillin in the Mammary Gland of the Bovine

University of Illinois, Urbana, Illinois

ABSTRACT

Antibiotics are generally administered to mastitis-infected animals via a solution or suspension manually infused into the infected quarter (s) of the udder. Current recommendations state that milk from antibiotic-treated cows should be discarded for 72 hr., or six milkings, after the last treatment. Questions have arisen concerning the possible presence or absence of antibiotics in the nontreated quarters following treatment.

Randall et al. (7) reported that milk from the untreated quarters of two cows showed the presence of chlortetracycline (aureomycin) and oxytetracycline (terramycin) following dosages of 426 and 852 mg. of each agent. Chlortetracycline persisted in the milk of the treated quarters for as long as 5 wk. and of the untreated quarters for a period of five days following treatment with the larger dosage levels. Following intramammary infusion of oxytetracycline ointment into two cows, the antibiotic could be detected in the milk from treated quarters for three to four days and from the untreated quarters for one day.

¹ Department of Dairy Science.

² Department of Food Technology.

³ College of Veterinary Medicine.