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Effect on Reproduction of Feeding Diethylstilbestrol to Dairy Cattle¹

Departments of Dairy Husbandry and of Zoology, Kansas Agricultural Experiment Station, Manhattan

ABSTRACT

Twenty-one cows from the Kansas State College purebred dairy herd and five pairs of identical-twin cows were used to determine the physiological effects of low-level diethylstilbestrol (DES) feeding on reproductive behavior. The cows were fed DES as part of their daily grain ration at levels of 0–20 mg. per 1,000 lb. of body weight.

Results indicate that the feeding of DES at levels ranging from 5 to 15 mg. had no adverse effect on estrous cycle, conception, or gestation. Three cows receiving the 20-mg. level of DES feeding aborted; however, several other cows fed at this level had no reproductive difficulty.

There were no observable detrimental side effects associated with DES feeding.

¹ Contributions No. 271 and 289. These data are taken in part from a thesis by the senior author presented to the Graduate School of Kansas State College of Agriculture and Applied Science, in partial fulfillment of the requirements for the degree of Master of Science. Supported in part by a grant from Eli Lilly and Company, Indianapolis, Indiana.

² Present address: Dairy Department, Mississippi State University, State College, Mississippi.