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Journal of Dairy Science Vol. 42 No. 4 671-678
© 1959 by American Dairy Science Association ®
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Effect of Chlortetracycline on Nutrient Utilization by Dairy Calves 1,2,

L. J. Bush3, R. S. Allen and N. L. Jacobson

Department of Animal Husbandry, Iowa State College, Ames

ABSTRACT

Sixteen male dairy calves were used to study the effect of chlortetracycline, fed at a level of 80 mg. per calf daily, on growth and nutrient utilization. The average weight gain during the 16-wk. experiment was 164 lb. for the antibiotic-fed calves and 145 lb. for the controls. Conventional digestion trials conducted during the fifth, eighth, and 11th weeks of the experiment gave little evidence that chlortetracycline has any effect on ash or nitrogen retention or upon the apparent digestibility of cellulose, protein, or dry matter. Neither observations on the disposition of orally administered Ca45 nor data from a concurrent total calcium balance study conducted during the 12th wk. gave any substantial evidence that chlortetracycline has any effect on calcium utilization. Measurement of bone growth, by use of radioautographs, from the time of Ca45 administration to sacrifice of the animals demonstrated that the greater weight gains of the antibiotic-fed calves were paralleled by greater skeletal development. The increased growth of the calves receiving the antibiotic was associated with increased feed consumption.

FOOTNOTES

1 Journal paper No. J-3517 of the Iowa Agricultural and Home Economies Experiment Station, Ames, Iowa. Project No. 1324.

2 This study was supported in part through funds provided by the American Cyanamid Company, New York, N. Y.

3 Present address: Dairy Department, Oklahoma State University, Stillwater.






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Copyright © 1959 by the American Dairy Science Association ®.