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Effect of Potassium Orotate and Methionine Alone and with Various Antibacterial Agents in a High Colostrum Diet for Young Calves¹

Department of Dairy Science, Florida Agricultural Experiment Station, Gainesville

ABSTRACT

Supplementary potassium orotate with methionine appeared to stimulate growth of yearling heifers (9) and young calves (10). Orotic acid per se also was effective as a growth promotant when fed with methionine to dairy calves (7). Orotic acid is a growth factor for some bacteria (1, 5). It is possible, therefore, that its effect on animal growth resulted indirectly from stimulation of symbiotic organisms. Dietary antibiotics (2) and other antobacterial agents (3, 8) also have increased growth rate in dairy calves, possible by inhibition of antagonistic microorganisms. Hence, an increase in the growth rate of calves may have resulted from stimulation of some organisms and depression of others. This experiment was designed to obtain information on the effect of feeding supplementary potassium orotate (a bacterial growth factor) simultaneously with various inhibitors of bacterial development under especially favorable environmental conditions.

Thirty-six new-born Guernsey and Jersey calves were allotted to six groups which were identical as to sex and breed and similar in weight and height at withers. The calves were managed and fed as in previous work (11).

¹ Florida Agricultural Experiment Station Journal Series No. 652.