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Hormonal Control of Mammary Growth and Lactation in the Goat¹

Department of Physiology and Pharmacology, Michigan State University, East Lansing

ABSTRACT

Mammary growth and lactation were induced in kids and mature goats by weekly injections of macrocrystalline stilbestrol alone, or of macrocrystalline progesterone and stilbestrol in combination at ratios of 40:1, 80.1, and 1.000:1. Sexually mature goats were distinctly more responsive to the treatments than 8-mo.-old goats. Although all groups reached approximately the same peak production 7 mo. from the start of the experiment, a more rapid onset of lactation was noted in those groups where progesterone and stilbestrol were combined in the treatment. Two goats approached closely the level of production recorded in the subsequent normal lactation. However, most of them were considerably below this level. No clear-cut indications were found for an optimum ratio between progesterone and estrogen for the induction of mammary growth and lactation in the goat.

¹ Published with the approval of the Director, Michigan Agricultural Experiment Station as Journal Series No. 2206.