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Effect of Oxytocin and Epinephrine on the Conception Rate of Cows

Department of Dairy Science, University of Illinois, Urbana

ABSTRACT

The effect on conception rate of injecting oxytocin just after, or epinephrine just before, natural mating and artificial insemination was tested with three groups of normal cows and two groups of "hard-to-settle" cows. Intravenous injections of 15 I.U. oxytocin within 5 min. after natural mating brought about a significant increase in conception in one group of normal cows (56 vs. 84% actual calvings). A similar trend (not statistically significant) was found with a second group of normal cows (48 vs. 56%) and with both groups of hard-to-settle cows (39 vs. 52% and 21 vs. 58%). An intravenous injection of 2 ml. of a 1/1000 solution of epinephrine within 5 min. before natural mating in one experiment resulted in an increase in the per cent of cows that conceived (controls 48 vs. treated 58%, not significant). The increase was similar to that shown by oxytocin injections. Neither oxytocin nor epinephrine treatment significantly affected conception rate in one group of artificially inseminated cows as compared to controls (controls 73 vs. oxytocin 67 vs. epinephrine 68%, 60- to 90-day nonreturns to service).